Topic: State of the Art in the Management of Oral Squamous Cell Carcinoma

This Special Issue is composed of 11 manuscripts focusing on particular aspects of the state of the art in oral squamous cell carcinoma (OSCC) under the light of current knowledge. An effort has been made to selectively approach particular aspects of OSCC management while selecting the most prominent series within the last 15 years. Some of the incoming works have made a special effort in trying to include and systematically analyze more relevant works according to a predetermined search, inclusion and exclusion criteria, with a particular PICO question and a flow chart, while others have made a general review according to subjective criteria based on authors´ own experience in selecting more relevant works. While the more systematically approach is more relevant in the evidence-based scale, reviews by selected experts still have a relevant role in the field of surgery. The approached fields are: (1) the role of human papillomavirus (HPV) in OSCC; (2) the role of sentinel node biopsy in the treatment of OSCC; (3) the influence of surgical resection margins in OSCC; (4) the role of radiotherapy in OSCC; (5) the role of elective neck dissection in early-staged OSCC; (6) the role of elective neck dissection in OSCC of the upper maxilla; (7) the role of contralateral neck dissection in OSCC; (8) the role of salvage surgery in recurrent OSCC; (9) the reliability of the combined-triangular full-thickness skin graft for covering the radial forearm free flap donor-site; (10) the prognosis and quality of life in head and neck cancer; (11) last but not least, a special article about the current role of the facial allograft transplantation. This and other compendiums of current knowledge about the disease may establish the baseline for further goals and achievements in the battle against oral cancer.

Oral squamous cell carcinoma, neck dissection, salvage surgery, radiotherapy, quality of life, facial transplantation

8 Jun 2016