REFERENCES
1. Gillespie TC, Sayegh HE, Brunelle CL, Daniell KM, Taghian AG. Breast cancer-related lymphedema: risk factors, precautionary measures, and treatments. Gland Surg 2018;7:379-403.
2. Armer JM, Radina ME, Porock D, Culbertson SD. Predicting breast cancer-related lymphedema using self-reported symptoms. Nurs Res 2003;52:370-9.
3. Fu MR, Rosedale M. Breast cancer survivors' experiences of lymphedema-related symptoms. J Pain Symptom Manage 2009;38:849-59.
4. Jørgensen MG, Hermann AP, Madsen AR, et al. Cellulitis is associated with severe breast cancer-related lymphedema: an observational study of tissue composition. Cancers 2021;13:3584.
5. Jørgensen MG, Toyserkani NM, Hansen FG, Bygum A, Sørensen JA. The impact of lymphedema on health-related quality of life up to 10 years after breast cancer treatment. NPJ Breast Cancer 2021;7:70.
6. Khan F, Amatya B, Pallant JF, Rajapaksa I. Factors associated with long-term functional outcomes and psychological sequelae in women after breast cancer. Breast 2012;21:314-20.
7. Boyages J, Xu Y, Kalfa S, et al. Financial cost of lymphedema borne by women with breast cancer. Psychooncology 2017;26:849-55.
8. Johnson AR, Asban A, Granoff MD, et al. Is Immediate lymphatic reconstruction cost-effective? Ann Surg 2021;274:e581-8.
9. Shaitelman SF, Cromwell KD, Rasmussen JC, et al. Recent progress in the treatment and prevention of cancer-related lymphedema. CA Cancer J Clin 2015;65:55-81.
10. Martínez-Jaimez P, Armora Verdú M, Forero CG, et al. Breast cancer-related lymphoedema: risk factors and prediction model. J Adv Nurs 2022;78:765-75.
11. Johnson AR, Kimball S, Epstein S, et al. Lymphedema incidence after axillary lymph node dissection: quantifying the impact of radiation and the lymphatic microsurgical preventive healing approach. Ann Plast Surg 2019;82:S234-41.
12. DiSipio T, Rye S, Newman B, Hayes S. Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis. Lancet Oncol 2013;14:500-15.
13. Hill WKF, Deban M, Platt A, Rojas-Garcia P, Jost E, Temple-Oberle C. Immediate lymphatic reconstruction during axillary node dissection for breast cancer: a systematic review and meta-analysis. Plast Reconstr Surg Glob Open 2022;10:e4291.
14. Pereira ACP, Koifman RJ, Bergmann A. Incidence and risk factors of lymphedema after breast cancer treatment: 10 years of follow-up. Breast 2017;36:67-73.
15. Montagna G, Zhang J, Sevilimedu V, et al. Risk factors and racial and ethnic disparities in patients with breast cancer-related lymphedema. JAMA Oncol 2022;8:1195-200.
16. Ahmad A. Breast Cancer Statistics: Recent Trends. In: Ahmad A, editor. Breast cancer metastasis and drug resistance. Cham: Springer International Publishing; 2019. pp. 1-7.
17. Schulze H, Nacke M, Gutenbrunner C, Hadamitzky C. Worldwide assessment of healthcare personnel dealing with lymphoedema. Health Econ Rev 2018;8:10.
18. Duhon BH, Phan TT, Taylor SL, Crescenzi RL, Rutkowski JM. Current mechanistic understandings of lymphedema and lipedema: tales of fluid, fat, and fibrosis. Int J Mol Sci 2022;23:6621.
19. Avraham T, Zampell JC, Yan A, et al. Th2 differentiation is necessary for soft tissue fibrosis and lymphatic dysfunction resulting from lymphedema. FASEB J 2013;27:1114-26.
20. Savetsky IL, Ghanta S, Gardenier JC, et al. Th2 cytokines inhibit lymphangiogenesis. PLoS One 2015;10:e0126908.
21. Ogata F, Fujiu K, Matsumoto S, et al. Excess lymphangiogenesis cooperatively induced by macrophages and CD4(+) T cells drives the pathogenesis of lymphedema. J Invest Dermatol 2016;136:706-14.
22. Baik JE, Park HJ, Kataru RP, et al. TGF-β1 mediates pathologic changes of secondary lymphedema by promoting fibrosis and inflammation. Clin Transl Med 2022;12:e758.
23. Hespe G, Nitti M, Mehrara B. Pathophysiology of lymphedema. Available from:
24. Aschen S, Zampell JC, Elhadad S, Weitman E, De Brot Andrade M, Mehrara BJ. Regulation of adipogenesis by lymphatic fluid stasis: part II. expression of adipose differentiation genes. Plast Reconstr Surg 2012;129:838-47.
25. Miaskowski C, Dodd M, Paul SM, et al. Lymphatic and angiogenic candidate genes predict the development of secondary lymphedema following breast cancer surgery. PLoS One 2013;8:e60164.
26. Finegold DN, Baty CJ, Knickelbein KZ, et al. Connexin 47 mutations increase risk for secondary lymphedema following breast cancer treatment. Clin Cancer Res 2012;18:2382-90.
27. Finegold DN, Schacht V, Kimak MA, et al. HGF and MET mutations in primary and secondary lymphedema. Lymphat Res Biol 2008;6:65-8.
28. Rockson SG, Keeley V, Kilbreath S, Szuba A, Towers A. Cancer-associated secondary lymphoedema. Nat Rev Dis Primers 2019;5:22.
29. Sudduth CL, Greene AK. Primary lymphedema: update on genetic basis and management. Adv Wound Care 2022;11:374-81.
30. Ahmed RL, Schmitz KH, Prizment AE, Folsom AR. Risk factors for lymphedema in breast cancer survivors, the iowa women's health study. Breast Cancer Res Treat 2011;130:981-91.
31. Tsai RJ, Dennis LK, Lynch CF, Snetselaar LG, Zamba GK, Scott-Conner C. The risk of developing arm lymphedema among breast cancer survivors: a meta-analysis of treatment factors. Ann Surg Oncol 2009;16:1959-72.
32. Yusof KM, Avery-Kiejda KA, Ahmad Suhaimi S, et al. Assessment of potential risk factors and skin ultrasound presentation associated with breast cancer-related lymphedema in long-term breast cancer survivors. Diagnostics 2021;11:1303.
33. Armer JM, Ballman KV, McCall L, et al. Factors associated with lymphedema in women with node-positive breast cancer treated with neoadjuvant chemotherapy and axillary dissection. JAMA Surg 2019;154:800-9.
34. Ariel IM, Resnick MI, Oropeza R. The effects of irradiation (external and internal) on lymphatic dynamics. Am J Roentgenol Radium Ther Nucl Med 1967;99:404-14.
35. LENZI M, BASSANI G. The effect of radiation on the lymph and on the lymph vessels. Radiology 1963;80:814-7.
36. Allam O, Park KE, Chandler L, et al. The impact of radiation on lymphedema: a review of the literature. Gland Surg 2020;9:596-602.
37. Warren LE, Miller CL, Horick N, et al. The impact of radiation therapy on the risk of lymphedema after treatment for breast cancer: a prospective cohort study. Int J Radiat Oncol Biol Phys 2014;88:565-71.
38. Manirakiza A, Irakoze L, Shui L, Manirakiza S, Ngendahayo L. Lymphoedema after breast cancer treatment is associated with higher body mass index: a systematic review and meta-analysis. East Afr Health Res J 2019;3:178-92.
39. Wu R, Huang X, Dong X, Zhang H, Zhuang L. Obese patients have higher risk of breast cancer-related lymphedema than overweight patients after breast cancer: a meta-analysis. Ann Transl Med 2019;7:172.
40. Ridner SH, Dietrich MS, Stewart BR, Armer JM. Body mass index and breast cancer treatment-related lymphedema. Support Care Cancer 2011;19:853-7.
41. Mehrara BJ, Greene AK. Lymphedema and obesity: is there a link? Plast Reconstr Surg 2014;134:154e-60e.
42. Zhu W, Li D, Li X, et al. Association between adjuvant docetaxel-based chemotherapy and breast cancer-related lymphedema. Anticancer Drugs 2017;28:350-5.
43. Hugenholtz-Wamsteker W, Robbeson C, Nijs J, Hoelen W, Meeus M. The effect of docetaxel on developing oedema in patients with breast cancer: a systematic review. Eur J Cancer Care 2016;25:269-79.
44. Kim M, Kim SW, Lee SU, et al. A model to estimate the risk of breast cancer-related lymphedema: combinations of treatment-related factors of the number of dissected axillary nodes, adjuvant chemotherapy, and radiation therapy. Int J Radiat Oncol Biol Phys 2013;86:498-503.
45. Cariati M, Bains SK, Grootendorst MR, et al. Adjuvant taxanes and the development of breast cancer-related arm lymphoedema. Br J Surg 2015;102:1071-8.
46. Kilbreath SL, Refshauge KM, Beith JM, et al. Risk factors for lymphoedema in women with breast cancer: a large prospective cohort. Breast 2016;28:29-36.
47. Swaroop MN, Ferguson CM, Horick NK, et al. Impact of adjuvant taxane-based chemotherapy on development of breast cancer-related lymphedema: results from a large prospective cohort. Breast Cancer Res Treat 2015;151:393-403.
48. Johnson AR, Granoff MD, Lee BT, Padera TP, Bouta EM, Singhal D. The impact of taxane-based chemotherapy on the lymphatic system. Ann Plast Surg 2019;82:S173-8.
49. Specht MC, Miller CL, Skolny MN, et al. Residual lymph node disease after neoadjuvant chemotherapy predicts an increased risk of lymphedema in node-positive breast cancer patients. Ann Surg Oncol 2013;20:2835-41.
50. Jung SY, Shin KH, Kim M, et al. Treatment factors affecting breast cancer-related lymphedema after systemic chemotherapy and radiotherapy in stage II/III breast cancer patients. Breast Cancer Res Treat 2014;148:91-8.
51. Wilke LG, McCall LM, Posther KE, et al. Surgical complications associated with sentinel lymph node biopsy: results from a prospective international cooperative group trial. Ann Surg Oncol 2006;13:491-500.
52. Kim M, Park IH, Lee KS, et al. Breast cancer-related lymphedema after neoadjuvant chemotherapy. Cancer Res Treat 2015;47:416-23.
53. Hayes SC, Janda M, Cornish B, Battistutta D, Newman B. Lymphedema after breast cancer: incidence, risk factors, and effect on upper body function. J Clin Oncol 2008;26:3536-42.
54. Shang T, Liang J, Kapron CM, Liu J. Pathophysiology of aged lymphatic vessels. Aging 2019;11:6602-13.
55. Kwan ML, Yao S, Lee VS, et al. Race/ethnicity, genetic ancestry, and breast cancer-related lymphedema in the pathways study. Breast Cancer Res Treat 2016;159:119-29.
56. Meeske KA, Sullivan-Halley J, Smith AW, et al. Risk factors for arm lymphedema following breast cancer diagnosis in Black women and White women. Breast Cancer Res Treat 2009;113:383-91.
57. Guliyeva G, Huayllani MT, Boczar D, Avila FR, Lu X, Forte AJ. Age as a risk factor for breast cancer-related lymphedema: a systematic review. J Cancer Surviv 2023;17:246-53.
58. Zou L, Liu FH, Shen PP, et al. The incidence and risk factors of related lymphedema for breast cancer survivors post-operation: a 2-year follow-up prospective cohort study. Breast Cancer 2018;25:309-14.
59. Byun HK, Kim JS, Chang JS, et al. Validation of a nomogram for predicting the risk of lymphedema following contemporary treatment for breast cancer: a large multi-institutional study (KROG 20-05). Breast Cancer Res Treat 2022;192:553-61.
60. Siotos C, Hassanein AH, Bello RJ, et al. Delayed breast reconstruction on patients with upper extremity lymphedema: a systematic review of the literature and pooled analysis. Ann Plast Surg 2018;81:730-5.
61. Basta MN, Fischer JP, Kanchwala SK, et al. A propensity-matched analysis of the influence of breast reconstruction on subsequent development of lymphedema. Plast Reconstr Surg 2015;136:134e-43e.
62. McLaughlin SA, Brunelle CL, Taghian A. Breast Cancer-related lymphedema: risk factors, screening, management, and the impact of locoregional treatment. J Clin Oncol 2020;38:2341-50.
63. Yamada Y. The studies on lymphatic venous anastomosis in lvmphedema. Available from: https://scholar.google.com/scholar?hl=zh-CN&as_sdt=0%2C5&q=Yamada+Y.+The+Studies+on+Lymphatic+Venous+Anastomosis+in+Lvmphedema.+Nagoya+J+Med+Sci.+1969%3B32%3A1-21.&btnG [Last accessed on 22 May 2023]
64. Boccardo F, Casabona F, De Cian F, et al. Lymphedema microsurgical preventive healing approach: a new technique for primary prevention of arm lymphedema after mastectomy. Ann Surg Oncol 2009;16:703-8.
65. Boccardo F, Casabona F, De Cian F, et al. Lymphatic microsurgical preventing healing approach (LYMPHA) for primary surgical prevention of breast cancer-related lymphedema: over 4 years follow-up. Microsurgery 2014;34:421-4.
67. Coriddi M, Mehrara B, Skoracki R, Singhal D, Dayan JH. Immediate lymphatic reconstruction: technical points and literature review. Plast Reconstr Surg Glob Open 2021;9:e3431.
68. Wiser I, Weinstein A, Kenworthy E, Mehrara B, Dayan J. Standardizing upper extremity indocyanine green lymphography in a lymphedema outpatient setting. Plast Reconstr Surg Glob Open 2020;8:45.
69. Spiguel L, Shaw C, Katz A, et al. Fluorescein isothiocyanate: a novel application for lymphatic surgery. Ann Plast Surg 2017;78:S296-8.
70. Russell PS, Velivolu R, Maldonado Zimbrón VE, et al. Fluorescent tracers for in vivo imaging of lymphatic targets. Front Pharmacol 2022;13:952581.
71. Abdallah M, Müllertz OO, Styles IK, et al. Lymphatic targeting by albumin-hitchhiking: Applications and optimisation. J Control Release 2020;327:117-28.
72. Trevaskis NL, Kaminskas LM, Porter CJ. From sewer to saviour - targeting the lymphatic system to promote drug exposure and activity. Nat Rev Drug Discov 2015;14:781-803.
73. Mele A, Fan B, Pardo J, et al. Axillary lymph node dissection in the era of immediate lymphatic reconstruction: Considerations for the breast surgeon. J Surg Oncol 2021;123:842-5.
74. Visconti G, Yamamoto T, Hayashi N, Hayashi A. Ultrasound-assisted lymphaticovenular anastomosis for the treatment of peripheral lymphedema. Plast Reconstr Surg 2017;139:1380e-1e.
75. Caretto AA, Stefanizzi G, Garganese G, et al. Treatment of early-stage gynecological cancer-related lower limb lymphedema by lymphaticovenular anastomosis-the triple incision approach. Medicina 2022;58:631.
76. Schwarz GS, Grobmyer SR, Djohan RS, et al. Axillary reverse mapping and lymphaticovenous bypass: Lymphedema prevention through enhanced lymphatic visualization and restoration of flow. J Surg Oncol 2019;120:160-7.
77. Gagne P, Sharma K. Relationship of common vascular anatomy to cannulated catheters. Int J Vasc Med 2017;2017:5157914.
78. Nomoto S, Hirakawa K, Ogawa R. Safety of copolyamide filler injection for breast augmentation. Plast Reconstr Surg Glob Open 2021;9:e3296.
79. Yamamoto T, Yamamoto N, Yamashita M, Furuya M, Hayashi A, Koshima I. Efferent lymphatic vessel anastomosis: supermicrosurgical efferent lymphatic vessel-to-venous anastomosis for the prophylactic treatment of subclinical lymphedema. Ann Plast Surg 2016;76:424-7.
80. Gentileschi S, Albanese R, Pino V, et al. SPECT/CT and fusion ultrasound to target the efferent groin lymph node for lymphatic surgery. Microsurgery 2019;39:605-12.
81. Gentileschi S, Servillo M, Garganese G, et al. The lymphatic superficial circumflex iliac vessels deep branch perforator flap: a new preventive approach to lower limb lymphedema after groin dissection-preliminary evidence. Microsurgery 2017;37:564-73.
82. Caretto AA, Stefanizzi G, Fragomeni SM, et al. Lymphatic function of the lower limb after groin dissection for vulvar cancer and reconstruction with lymphatic SCIP flap. Cancers 2022;14:1076.
83. Samra F, Sobti N, Nelson JA, Allen RJ Jr, Mehrara B, Dayan JH. Frontiers in oncologic reconstruction. Plast Reconstr Surg Glob Open 2019;7:e2181.
84. Chen WF, Knackstedt R. Delayed distally based prophylactic lymphaticovenular anastomosis: improved functionality, feasibility, and oncologic safety? J Reconstr Microsurg 2020;36:e1-2.
85. Johnson AR, Otenti D, Bates K, et al. Creating a policy for coverage of lymphatic surgery: addressing a critical unmet need. Plast Reconstr Surg 2023;10.1097/prs.0000000000010239.
86. Johnson AR, Fleishman A, Tran BNN, et al. Developing a lymphatic surgery program: a first-year review. Plast Reconstr Surg 2019;144:975e-85e.
87. Bracaglia R, D'Ettorre M, Gentileschi S, Tambasco D. Was the surgeon a satisfactory informant? Aesthet Surg J 2014;34:632-5.
88. Sappey M, Karmanski A, Beau E, Bry A. Anatomie, Physiologie, Pathologie de Vaisseaux Lymphatiques. Adrain Delahaye, Imprimerie de E. Martinet; 1874. Available from: https://archive.org/details/BIUSante_01562/page/n1/mode/2up [Last accessed on 22 May 2023]
89. Suami H. Lymphosome concept: Anatomical study of the lymphatic system. J Surg Oncol 2017;115:13-7.
90. Suami H, Scaglioni MF. Anatomy of the lymphatic system and the lymphosome concept with reference to lymphedema. Semin Plast Surg 2018;32:5-11.
91. Tourani SS, Taylor GI, Ashton MW. Anatomy of the superficial lymphatics of the abdominal wall and the upper thigh and its implications in lymphatic microsurgery. J Plast Reconstr Aesthet Surg 2013;66:1390-5.
92. Johnson AR, Bravo MG, James TA, Suami H, Lee BT, Singhal D. The all but forgotten mascagni-sappey pathway: learning from immediate lymphatic reconstruction. J Reconstr Microsurg 2020;36:28-31.
93. Kubik S. The role of the lateral upper arm bundle and the lymphatic watersheds in the formation of collateral pathways in lymphedema. Acta bio Acad Sci Hung 1980;31:191-200.
94. Johnson AR, Granoff MD, Suami H, Lee BT, Singhal D. Real-time visualization of the mascagni-sappey pathway utilizing ICG lymphography. Cancers 2020;12:1195.
95. Ciucci J. Derivative lymphatic currents UL, Ciucci, JL - English. In: Linfedema Del Miembro Superior Postratamiento Del Cancer de Mama. Nayarit Ed; 2004:29. Available from: https://linfedemahoy.com/linfedema-de-miembro-superior [Last accessed on 22 May 2023]
96. Latorre J, Ciucci JL, Rosendo A, et al. Anatomía Del Sistema Linfático Del Miembro Superior Revisión. Available from: https://filadd.com [Last accessed on 22 May 2023]
97. Ciucci JL, Vadra GD, Sorocco J. Investigación anatómica del drenaje linfático del miembro superior. Su importancia en la patología traumatológica. Available from: https://www.aaot.org.ar/revista/1993_2002/1997/1997_4/620413.pdf [Last accessed on 22 May 2023]
98. Amore M, Tapia L, Mercado D, Pattarone G, Ciucci J. Lymphedema: a general outline of its anatomical base. J Reconstr Microsurg 2016;32:2-9.
99. Friedman R, Bustos VP, Pardo J, et al. Superficial and functional imaging of the tricipital lymphatic pathway: a modern reintroduction. Breast Cancer Res Treat 2023;197:235-42.
100. Granoff MD, Pardo JA, Johnson AR, et al. Superficial and functional lymphatic anatomy of the upper extremity. Plast Reconstr Surg 2022;150:900-7.
101. Granoff MD, Pardo J, Shillue K, et al. Variable anatomy of the lateral upper arm lymphatic channel: a potential anatomic risk factor for the development of breast cancer related lymphedema. Plast Reconstr Surg 2023; doi: 10.1097/prs.0000000000010245.
102. Paramanandam VS, Dylke E, Clark GM, et al. Prophylactic use of compression sleeves reduces the incidence of arm swelling in women at high risk of breast cancer-related lymphedema: a randomized controlled trial. J Clin Oncol 2022;40:2004-12.
103. Koelmeyer LA, Thompson BM, Mackie H, et al. Personalizing conservative lymphedema management using indocyanine green-guided manual lymphatic drainage. Lymphat Res Biol 2021;19:56-65.
104. Gross JP, Sachdev S, Helenowski IB, et al. Radiation therapy field design and lymphedema risk after regional nodal irradiation for breast cancer. Int J Radiat Oncol Biol Phys 2018;102:71-8.
105. Brown S, Dayan JH, Coriddi M, et al. Pharmacological treatment of secondary lymphedema. Front Pharmacol 2022;13:828513.
