fig2

Figure 2. Images from top of the head in females. The top of the head is illustrated in seven females complaining of hair loss. The upper panels show clinical perception as: “No Pattern” (left; 1 case); FPHL graded as LI (1 case), LII (2 cases) or LIII (2 cases) and one subject with no clear evidence for patterning (Other; 1 case). From top to bottom, the panels show hair combed in spokes of a wheel, with a parted midline and with the clipped hair site. The latter is highlighted as a white empty circle. The region of interest (ROI) outline, located at a distance from the epicentre, was then transposed on the other views (top 2 rows). Note again that top of the head views did not include the frontal margin, which does not influence the scalp coverage scoring (SCS). When required according to the study protocol, the clinician measured scalp coverage in vivo (SCS in vivo; described in the next section), while charge coupled device images (source document) were used at a later stage to evaluate scalp coverage scoring on the computer screen (see next section). A third view was recorded to document precisely the topography of the ROI that was selected by the clinician not only at the preferred location, i.e., leading edge of the balding process, but also in agreement with the acceptance by the patient. This ROI might be either clinically unaffected or clinically invaded by the extension of a clearly visible balding process, as illustrated typically in HIII-HV [Figure 1] and LII and LIII [Figure 2]. The ROI was subject to detailed scalp hair functional evaluation with our phototrichogram method (as detailed below). FPHL: Female pattern hair loss.