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Figure 2. Skincare regimen in combination with pulsed-laser phototherapy [intense pulsed light (IPL)]. 46-year-old Fitzpatrick II Italian-portuguese female seeking perioral rejuvenation before (left) and after (right) a combination of daily skincare regimen (topical retinoid, vitamin C, and hydroquinone), hyaluronic acid filler to treat the upper lip rhytids, IPL for three sessions, microneedling to a 2 mm depth