Topic: State of the Art in the Management of Oral Squamous Cell Carcinoma

Download All Articles

A special issue of Plastic and Aesthetic Research  (Print ISSN:2347-9264; Online ISSN:2349-6150).

Deadline for manuscript submissions: 8 Jun 2016

Share This Special Issue

Guest Editor(s)

  • Prof. Raúl González-García, MD, PhD, FEBOMFS
    Department of Oral and Maxillofacial-Head and Neck Surgery, University Hospital Infanta Cristina, 06080 Badajoz, Spain.

    E-mail

Special Issue Introduction:

This special issue is composed of eleven manuscripts focusing on particular aspects about the state of the art in oral squamous cell carcinoma (OSCC) under the light of current knowledge. An effort has been made to selectively approach particular aspects of OSCC management, while selecting the most prominent series within the last 15 years. Some of the incoming works have made a special effort in trying to include and systematically analyze more relevant works according to a predetermined search, inclusion and exclusion criteria, with a particular PICO question and a flow chart, while others have made a general review according to subjective criteria based on authors´ own experience in selecting more relevant works. While the more systematically approach is more relevant in the evidence-based scale, reviews by selected experts still have a relevant role in the field of surgery. The approached fields are: (1) the role of human papillomavirus (HPV) in OSCC; (2) the role of sentinel node biopsy in the treatment of OSCC; (3) the influence of surgical resection margins in OSCC; (4) the role of radiotherapy in OSCC; (5) the role of elective neck dissection in early-staged OSCC; (6) the role of elective neck dissection in OSCC of the upper maxilla; (7) the role of contralateral neck dissection in OSCC; (8) the role of salvage surgery in recurrent OSCC; (9) the reliability of the combined-triangular full-thickness skin graft for covering the radial forearm free flap donor-site; (10) the prognosis and quality of life in head and neck cancer; and last but not least a special article about (11) the current role of the facial allograft transplantation. This and other compendiums of current knowledge about the disease may establish the baseline for further goals and achievements in the battle against oral cancer.

Keywords:

Oral squamous cell carcinoma, neck dissection, salvage surgery, radiotherapy, quality of life, facial transplantation

Submission Information:

For Author Instructions, please refer to http://parjournal.net/pages/view/author_instructions
For Online Submission, please login at http://www.editorialmanager.com/paar/default.aspx
Submission Deadline: 8 Jun 2016
Contacts: Smart Zhang, Managing Editor, editor002@parjournal.net

Published Articles Download All Articles
  • Current role in facial allograft transplantation: what have we learned?

    Pedro Infante-Cossio , Fernando Barrera-Pulido , Tomas Gomez-Cia , Domingo Sicilia-Castro , Alberto Garcia-Perla-Garcia , Purificacion Gacto-Sanchez , Jose-Maria Hernandez-Guisado , Araceli Lagares-Borrego , Rocio Narros-Gimenez , Juan-David Gonzalez-Padilla
    Face transplant (FT) has evolved enormously in the last 10 years since the successful completion of the first facial transplant. This procedure has become a new reconstructive option for complex facial deformities to restore the anatomy of patients with severely disfigured faces. The authors review the literature and discuss the main surgical, immunological, and ethical aspects as well as the results described in patients undergoing FT. To date there have been more than thirty FT worldwide. The main indication was post-traumatic deformity. In all cases a standard immunosuppression was... Read more
    Plast Aesthet Res 2016;3:211-8. | doi:10.20517/2347-9264.2016.11
    Published on: 24 Jun 2016  | Viewed:28857  | Downloaded:457
    +HTML| PDF
  • Contralateral neck dissection in oral squamous cell carcinoma: when it should be done?

    Laura Villanueva-Alcojol
    Oral cavity squamous cell carcinoma (OSCC) has a high incidence of cervical micrometastases and sometimes metastasizes bilaterally because of the rich lymphatics in the submucosal plexus, which freely communicate across the midline. The presence of contralateral pathologic lymph nodes has been reported previously as a critical factor influencing the survival of patients. There are a few reports in the literature with regard to the rates of contralateral neck disease and the factors that may be involved in the risk with them. An elective ipsilateral neck treatment is generally recommended... Read more
    Plast Aesthet Res 2016;3:181-8. | doi:10.20517/2347-9264.2016.14
    Published on: 24 Jun 2016  | Viewed:3459  | Downloaded:227
    +HTML| PDF
  • Elective neck dissection in oral squamous cell carcinoma of the upper maxilla: necessary?

    Manuel Moreno-Sánchez
    Aim: Surgical treatment of clinically negative neck in maxillary squamous cell carcinoma (SCC) of the upper jaw is controversial. The purpose of this systematic review was to define the incidence of cervical metastasis and to assess if elective neck dissection is justified when the neck is not primarily affected. Methods: An electronic literature search was conducted in several databases, including MEDLINE, EMBASE, and Cochrane Central databases, for articles written in English. Results: Twenty-eight articles were included in the review. The overall cervical metastases rate was 33% and the... Read more
    Plast Aesthet Res 2016;3:175-80. | doi:10.20517/2347-9264.2016.18
    Published on: 24 Jun 2016  | Viewed:7671  | Downloaded:156
    +HTML| PDF
  • Current prognosis and quality of life following surgical treatment for head and neck squamous cell carcinoma

    Cristina Hernández-Vila
    Head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers in the world with a close relation with some risk factor like, tobacco, alcohol consumption and more recently, with human papilloma virus infection. A review of the literature about actual prognosis and quality of life in HNSCC has been done analysing the results of surgical treatment and their impact on the quality of life of patients. Despite the elevated incidence of HNSCC, the survival rate has increased considerably over the last years thanks to the development of new surgical techniques, such as,... Read more
    Plast Aesthet Res 2016;3:203-10. | doi:10.20517/2347-9264.2016.20
    Published on: 24 Jun 2016  | Viewed:17737  | Downloaded:364
    +HTML| PDF
  • The reliability of the "Iberic graft" for covering of the radial forearm free flap donor site

    Manuel Moreno-Sánchez , Raúl González-García
    Aim: Traditional donor site closure from radial forearm free flap (RFFF) has been associated with esthetic and functional morbidity. To avoid complications, such as color mismatch and secondary donor site morbidity, a new technique named "Iberic graft" for covering the RFFF donor site was described previously by our team. Methods: A study of patients who underwent reconstruction of head and neck defects using a RFFF was conducted to assess postoperative complications of the RFFF donor site and also to evaluate the morbidity in terms of aesthetics and function following the use of the... Read more
    Plast Aesthet Res 2016;3:197-202. | doi:10.20517/2347-9264.2016.21
    Published on: 24 Jun 2016  | Viewed:11407  | Downloaded:5193
    +HTML| PDF
  • The role of salvage surgery in oral squamous cell carcinoma

    Raúl González-García
    Aim: To select and analyze the most representative papers published in the literature concerning oral squamous cell carcinoma (OSCC), specifically dealing with salvage surgery following primary treatment by surgery with or without by postoperative radiotherapy, specifically focusing in the oral cavity and oropharynx locations. Methods: A bibliography search on MEDLINE and EMBASE databases for studies published from March 2000 to March 2016 was conducted. The authors only included studies published in the English language and those dealing with “squamous cell carcinoma of the oral cavity... Read more
    Plast Aesthet Res 2016;3:189-96. | doi:10.20517/2347-9264.2016.43
    Published on: 24 Jun 2016  | Viewed:15523  | Downloaded:147
    +HTML| PDF
  • Elective neck dissection in early oral squamous cell carcinoma: necessary?

    Carlos Moreno-García
    Aim: The indication of neck dissection in oral squamous cell carcinoma (OSCC) is a problem of risk-benefit evaluation between probability of neck metastases, the problem of complications associated with neck dissection and the prognostic influence of delayed diagnosis of metastasis during follow-up. There is no consensus on the elective treatment of the neck in early oral cancer patients with a clinically N0 (cN0) neck. Methods: The author performed a search of PubMed articles with the words "elective neck dissection vs. observation", "node negative neck" and "early stage oral squamous cell... Read more
    Plast Aesthet Res 2016;3:167-74. | doi:10.20517/2347-9264.2016.12
    Published on: 25 May 2016  | Viewed:72204  | Downloaded:284
    +HTML| PDF
  • The role of radiotherapy in the treatment of oral cavity cancer

    Joaquín J. Cabrera-Rodríguez
    Radiotherapy plays a critical role in the treatment of oral cavity squamous cell carcinoma as monotherapy in early stage cancer or combined with surgery and/or chemotherapy in advances ones. Recent developments in the imaging of cancer and radiation technology have allowed developing more precise delivery of treatment with recent data demonstrating improvement in survival and lessening of adverse toxics effects of radiation. This review will focus in the recent advances and current state-of-the-art in radiation oncology both external beam radiotherapy and brachytherapy. As complexity of... Read more
    Plast Aesthet Res 2016;3:158-66. | doi:10.20517/2347-9264.2016.13
    Published on: 25 May 2016  | Viewed:13015  | Downloaded:532
    +HTML| PDF
  • The role of human papillomavirus in oral squamous cell carcinoma

    Francisco A. Ramírez-Pérez
    Aim: The causative role of human papillomavirus (HPV) has been established into the aetiology of oral squamous cell carcinoma (OSCC). Some authors believe that HPV can determinate the prognosis and module treatment response from this kind of malignancies. Methods: Articles published in the last 10 years, focusing on the role of HPV in the development, molecular biology, prognosis and treatment of OSCC were reviewed. Results: Thirty-nine articles from 252 were selected, highlighting 4 meta-analysis, 3 prospective and 2 retrospective studies. According to its role in the development of... Read more
    Plast Aesthet Res 2016;3:132-41. | doi:10.20517/2347-9264.2016.17
    Published on: 25 May 2016  | Viewed:10874  | Downloaded:186
    +HTML| PDF
  • The role of sentinel node biopsy in oral squamous cell carcinoma

    Justo Serrano-Vicente
    Aim: The purpose of this study was to conduct a systematic review of the published literature to assess the state of the art of this procedure. Sentinel node biopsy (SNB) in oral squamous cell cancer (OSCC) is a novel and proven useful technique alternative to the neck dissection (ND) in the management of OSCC. Methods: The authors searched PubMed for literature in English published for the last five years, addressing this topic. Prospective studies articles were selected with at least thirty patients studied. Results: Of 235 studies found, 14 studies met the exclusion and inclusion... Read more
    Plast Aesthet Res 2016;3:142-9. | doi:10.20517/2347-9264.2016.19
    Published on: 25 May 2016  | Viewed:5839  | Downloaded:136
    +HTML| PDF
  • The tissue shrinkage phenomenon on surgical margins in oral and oropharyngeal squamous cell carcinoma

    David González-Ballester
    Aim: One of the most important factors associated with recurrence rate and overall survival is the status of surgical margin of resection free of disease. However, sometimes, the margins measured intra-operatively at the time of surgery differ of those measured by the pathologist in the histopathologic analysis. Faced with this dilemma, a literature review of the best available evidence was conducted in an attempt to determine how the phenomenon of tissue shrinkage may influence on the surgical margin of resection in patients undergoing oral and oropharyngeal squamous cell carcinoma (SCC).... Read more
    Plast Aesthet Res 2016;3:150-7. | doi:10.20517/2347-9264.2016.23
    Published on: 25 May 2016  | Viewed:3468  | Downloaded:187
    +HTML| PDF
  • State of the art in the management of oral squamous cell carcinoma

    Raúl González-García
    The present editorial is an introductory paper to a special issue composed of eleven manuscripts focusing on particular aspects about the state of the art in OSCC under the light of current knowledge. While strict criteria for systematic reviewing concerning Cochrane database recommendations have not been followed due to the heterogeneity of the revised series, an effort has been made to selectively approach particular aspects of OSCC management, while selecting the most prominent series within the last 15 years. Some of the incoming works have made a special effort in trying to include and... Read more
    Plast Aesthet Res 2016;3:129-31. | doi:10.20517/2347-9264.2016.30
    Published on: 25 May 2016  | Viewed:16899  | Downloaded:156
    +HTML| PDF
Plastic and Aesthetic Research ISSN 2349-6150 (Online), ISSN 2347-9264 (Print)
Partners
Copyright © 2018 OAE Publishing Inc. All Rights Reserved.