Editor's Picks
  • Original Article

    Modulation of Wnt/β-catenin signaling affects the directional differentiation of hair follicle stem cells

    Bin Yang , Xiao-Ying Wu , Jian Ni , Bing-Hang Li , Li-Huan Deng , Meng-Juan Xiang
    Aim: The differentiation of hair follicle stem cells (HFSCs) into hair follicle cells has potential clinical applications for cutaneous burns. However, the mechanisms regulating the differentiation of HFSCs into hair follicular papilla or epidermal cells are currently not clear. This study investigated the role of the Wnt/β-catenin pathway and its crosstalk with other signaling components during this differentiation process. Methods: Lithium chloride (LiCl, 10 mmol/L) and keratinocyte growth factor (KGF, 10 µg/L) were used to induce HFSC...
    Published on: 29 Feb 2016
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  • Topic: Aesthetic Surgery of the Breast

    Internal bra: a unifying solution for reconstructive and aesthetic breast surgery issues

    Richard A. Baxter
    The internal bra is a concept utilizing implantable materials for long term maintenance of support and shape of the breast with mastopexy and in revision breast surgery. This article reviews the various materials used for the internal bra including Acellular Dermal Matrices, non-absorbable meshes, and newer bio-inductive products such as Seri silk scaffold and Galaflex.
    Published on: 15 Jan 2016
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  • Editorial

    Lift of cheek and neck: technical notes

    Maurice Yves Mommaerts
    Published on: 12 Nov 2015
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  • Review

    Nasal dorsal aesthetic lines and rhinoplasty technical tricks

    Alexander Kutubidze
    Rhinoplasty surgery remains one of the most difficult operations of the face. Improving aesthetic appearance and maintaining nasal function are inseparable goals in rhinoplasty surgery, and failure to achieve either of these objectives can be devastating for the patient. After evaluating a variety of rhinoplasty complications, increased attention was devoted to the surgical technique for reconstruction of the dorsal aesthetic lines and nasal tip projection in the patient with a prominent dorsal hump. Based on the modern concept of cartilage...
    Published on: 12 Nov 2015
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  • Original Article

    Cost-effectiveness of one-stage versus two-stage breast reconstruction in the United Kingdom

    Isabel Teo , Iman A. Azmy
    Aim: Permanent expanders allow for breast reconstruction as a single stage. These prostheses are more expensive than conventional tissue expanders, but this excess cost is markedly offset as only one operation is required. However, if the revision rate is sufficiently high, then this effect is negated. We aim to compare costs of one-stage vs. two-stage reconstruction at a single center, taking into account explantation and unexpected admissions following complications. Methods: A retrospective review was carried out on all patients who...
    Published on: 12 Nov 2015
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  • Original Article

    First-year experience of a new skin bank in Brazil

    Alysson Rogerio Matioski , Clóvis Rodrigo Guimarães Braz Pereira da Silva , Diogo Rodrigues da Silva-Cunha , Luiz Henrique Auerswald Calomeno , Flávia Thaiana Bonato , Marcelus Vinícios Araujo Nigro
    Aim: To report the 1st year experience of the skin bank opened at the Evangelical University Hospital of Curitiba (HUEC), Brazil in June 2013. Methods: A retrospective statistical and epidemiological study was conducted from data obtained from the activities of the HUEC skin bank from June 2013 to August 2014. Results: The HUEC skin bank harvested tissue from 45 cadaveric donors (46.6% female and 53.3% male), with an average age of 36.42. The white skin‑colored donors represented 91% of donations. Most causes of death were of neurological...
    Published on: 12 Nov 2015
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  • Original Article

    Synergistic effect of hyperbaric oxygen preconditioning and hydrogen-rich saline in ameliorating rat flap ischemia/reperfusion injury

    Yi-Ding Xiao , Yun-Qi Liu , Ming-Zi Zhang , You-Bin Wang , Yi-Fang Liu , Xue-Mei Ma
    Hyperbaric oxygen (HBO) treatment has been widely used in clinical work, while, hydrogen-rich saline (HRS) has also been shown its protective effect of ameliorating ischemia/reperfusion (IR) injury. What will we obtain if these two approaches combined together? In this study, we set five independent groups (Sham, IR, HBO, HRS and HBO+HRS) of rat abdominal skin flap IR model with different interferences. In conclusion, the synergistic application of HBO and HRS showed a higher flap survival rate, which could be a combined treatment to improve...
    Published on: 12 Nov 2015
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  • Original Article

    Tissue engineering using mesenchymal stem cells with periosteal wrap for bone defect repair in rabbits

    Trung-Hau Lê Thua , Dang-Nhat Pham , Khanh-Linh Lê , Minh-Tuan Lê , Quang-Ton-Quyen Nguyen , Phan-Huy Nguyen , Ngoc-Vu Tran , Ngoc-Luong Nguyen , Willy Boeckx , Albert Demey
    Aim: Mesenchymal stem cells (MSCs) are an excellent potential source of cells for bone tissue engineering due to their excellent renewal ability and osteogenic differentiation capabilities. This study was designed to evaluate the bone formation properties of a demineralized cancellous bone scaffold seeded with MSCs, with or without periosteum, in a critical size bone defect model in rabbits. Methods: Rabbit culture‑expanded bone marrow (BM)‑MSCs were seeded onto a human demineralized cancellous bone (HDCB) scaffold. Bone defects measuring 15...
    Published on: 12 Nov 2015
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