fig2

Figure 2. (A) Filler injections after radiofrequency (RF) treatment results in volumization. N: normal; F: Glytone 3 filler injection; RF30s+F: RF treatment for 30 s, RF60s+F: RF treatment for 60 s, both before filler injections through tunneling method; T+F: filler injected after tunneling without RF treatment for 30 s. (B) "*" sign indicates areas injected with fillers. Extracellular matrix components stained with Masson's trichrome show the treatment with both filler and RF enhances collagen bundle deposition (blue) and fibroplasia (red) Dermis stained with Verhoeff-Van Gieson shows that RF treatment resulted in shorter elastin fibers ("arrow" sign). Image used with permission.^[3]